免疫低下患者,如血液肿瘤、癌症化疗,可能发生中性粒细胞缺乏伴发热。这一人群,病原菌和感染灶常不明确,发热可能是严重潜在感染的唯一征象,出现临床表现后需尽早抗菌治疗,避免感染迅速进展。目前,国内外多篇关于中性粒细胞缺乏伴发热管理指南共识已发表,其中总结了相关定义、临床特征、流行病学、防治等内容。
中文及其解读:
1. 中国中性粒细胞缺乏伴发热患者抗菌药物临床应用指南(2020年版)
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发布者:中华医学会血液学分会(CMA,CHINESE MEDICAL ASSOCIATION),中国医师协会血液科医师分会
发布时间:2020-12-30
相关解读:《中国中性粒细胞缺乏伴发热患者抗菌药物临床应用指南(2020年版)》解读
[原文链接]
发布者:中国医学科学院血液病医院 陈欣,冯四洲
发布时间:2021-09-10
2. 肿瘤化疗导致的中性粒细胞减少诊治专家共识(2019 年版)
[原文链接]
发布者:中国抗癌协会肿瘤临床化疗专业委员会,中国抗癌协会肿瘤支持治疗专业委员会
发布时间: 2019-11-02
3. 中国中性粒细胞缺乏伴发热患者抗菌药物临床应用指南(2016年版)
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发布者:中华医学会血液学分会(CMA,CHINESE MEDICAL ASSOCIATION),中国医师协会血液科医师分会
发布时间: 2016-05-20
4. 中国中性粒细胞缺乏伴发热患者抗菌药物临床应用指南
[原文链接]
发布者:中华医学会血液学分会(CMA,CHINESE MEDICAL ASSOCIATION),中国医师协会血液科医师分会
发布时间:2012-08-01
英文及中文解读:
1. The Dutch Working Party on Antibiotic Policy (SWAB) Recommendations for the Diagnosis and Management of Febrile Neutropenia in Patients with Cancer
2022 SWAB建议:癌症患者发热性中性粒细胞减少症的诊断和治疗
[原文链接]
发布者:荷兰抗生素政策工作组(SWAB,Dutch Working Party on Antibiotic Policy)
发布时间:2022-10-14
2. Executive summary of the consensus document of the Spanish Society of Infectious Diseases and Clinical Microbiology (SEIMC), the Spanish Network for Research in Infectious Diseases (REIPI) and the Spanish Society of Haematology and Haemothe
SEIMC共识文件:血液恶性肿瘤患者发热性中性粒细胞减少症的管理(概要)
[原文链接]
发布者:西班牙临床微生物和传染病学会(SEIMC,Spanish Society of Clinical Microbiologyand Infectious Diseases)
发布时间:2019-03-26
3. Management of sepsis in neutropenic cancer patients: 2018 guidelines from the Infectious Diseases Working Party (AGIHO) and Intensive Care Working Party (iCHOP) of the German Society of Hematology and Medical Oncology (DGHO)
DGHO指南:中性粒细胞缺乏癌症患者脓毒症管理
[原文链接]
发布者:德国血液学和肿瘤学学会(DGHO,German Society of Hematology and Oncology)
发布时间:2019-02-22
4. SEOM clinical practice guideline: management and prevention of febrile neutropenia in adults with solid tumors (2018)
SEOM临床实践指南:成人实体瘤患者粒缺伴发热的治疗和预防
[原文链接]
发布者:西班牙肿瘤内科学会 (SEOM, Spanish Society of Medical Oncology)
发布时间:2018-11-23
5. Outpatient Management of Fever and Neutropenia in Adults Treated for Malignancy: American Society of Clinical Oncology and Infectious Diseases Society of America Clinical Practice Guideline Update
ASCO指南更新:成人恶性肿瘤患者中性粒细胞减少伴发热门诊管理
[原文链接]
发布者:美国临床肿瘤学会(ASCO,American Society of Clinical Oncology), 美国感染病学会(IDSA,Infectious Diseases Society of America)
发布时间:2018-02-20
6. Diagnosis and empirical treatment of fever of unknown origin (FUO) in adult neutropenic patients: guidelines of the Infectious Diseases Working Party (AGIHO) of the German Society of Hematology and Medical Oncology (DGHO)
DGHO指南:成人中性粒细胞缺乏患者未明发热诊断与经验治疗
[原文链接]
发布者:德国血液学和肿瘤学学会(DGHO,German Society of Hematology and Oncology)
发布时间:2017-08-30
7. Update-Guideline for the Management of Fever and Neutropenia in Children With Cancer and Hematopoietic Stem-Cell Transplantation Recipients
ASCO指南更新:儿童癌症或接受造血干细胞移植手术患者粒细胞减少伴发热管理
[原文链接]
发布者:美国临床肿瘤学会(ASCO,American Society of Clinical Oncology)
发布时间:2017-05-01
8. Antimicrobial Prophylaxis and Outpatient Management of Fever and Neutropenia in Adults Treated for Malignancy:American Society of Clinical Oncology Clinical Practice Guideline
ASCO:成人恶性肿瘤中性粒细胞减少伴发热抗菌药物预防和门诊管理临床指南
[原文链接]
发布者:美国临床肿瘤学会(ASCO,American Society of Clinical Oncology)
发布时间:2017-01-08
9. Management of febrile neutropaenia: ESMO Clinical Practice Guidelines
ESMO临床实践指南:发热性中性粒细胞减少的管理
[原文链接]
发布者:欧洲肿瘤内科学会(ESMO,European Society for Medical Oncology)
发布时间:2016-09-20
10. Diagnosis and antimicrobial therapy of lung infiltrates in febrile neutropenic patients (allogeneic SCT excluded): updated guidelines of the Infectious Diseases Working Party (AGIHO) of the German Society of Hematology and Medical Oncology DGHO)
德国发热性中性粒细胞减少症伴肺浸润的诊断和抗生素治疗指南(更新版)
[原文链接]
发布者:德国血液学和肿瘤学学会(DGHO,German Society of Hematology and Oncology)
发布时间:2015-01-01
相关解读:发热性中性粒细胞减少症伴肺浸润的诊断和抗生素治疗(异基因造血干细胞移植除外):2015德国血液肿瘤学会感染性疾病工作组(AGIHO)更新指南解读
[原文链接]
发布者:河北医科大学第二医院感染性疾病科 郭宪立 宋宁 贾伟华 袁胜芳
发布时间:2016-01-05
11. European guidelines for empirical antibacterial therapy for febrile neutropenic patients in the era of growing resistance: summary of the 2011 4th European Conference on Infections in Leukemia
第4届欧洲白血病感染会议(ECIL):细菌耐药时代中性粒细胞减少症患者发热经验治疗指南概要
[原文链接]
发布者:欧洲临床微生物与感染性疾病学会(ESCMID,European Society of Clinical Microbiology and Infectious Diseases
发布时间:2013-12-15
12. Guidelines for Management of Children With Fever and Neutropenia.
儿童发热和中性粒细胞减少的管理指南
[原文链接]
发布者:国际儿科粒缺伴发热专家组
发布时间:2013-09-01
13. Guideline for the Management of Fever and Neutropenia in Children With Cancer and/or Undergoing Hematopoietic Stem-Cell Transplantation
ASCO:癌症或接受造血干细胞移植手术的儿童中性粒细胞减少伴发热管理指南
[原文链接]
发布者:美国临床肿瘤学会(ASCO,American Society of Clinical Oncology)
发布时间:2012-09-17
14. Clinical Practice Guideline for the Use of Antimicrobial Agents in Neutropenic Patients with Cancer: 2010 Update by the Infectious Diseases Society of America
IDSA临床实践指南:中性粒细胞减少肿瘤患者抗菌药物应用
[原文链接]
发布者:美国感染病学会(IDSA,Infectious Diseases Society of America)
发布时间:2011-02-15